Marni D. Boppart, Sc.D.
Department of Kinesiology and Community Health
College of Applied Health Sciences
University of Illinois at Urbana-Champaign
Beckman Institute for Advanced Science and Technology
Download Curriculum Vitae (PDF)
Research: Molecular Muscle Physiology
Sc.D. Applied Anatomy and Physiology, Boston University, 2000
Research and Professional Interests
Professor Boppart's area of professional interest involves understanding the molecular and cellular adaptations to exercise, mechanical loading,
and exercise training. Counteracting the loss of skeletal muscle due to disease or aging using exercise therapy or molecular-based interventions is
essential for increasing both our quality of life and examining our limits of human performance. Our research focuses on examining the role of the
a7b1 integrin as a mechanosensor that regulates cellular signaling and protects against skeletal muscle injury. We are currently using a combination
of in vivo and in vitro models to determine the potential role of the integrin and other extracellular matrix proteins in the:
- mechanotransduction of cellular signaling
- protection from muscle disease (muscular dystrophy, cancer cachexia, insulin resistance)
- protection from exercise-induced muscle injury (repeat bout effect)
- recruitment and activation of adult stem cells
- aging process
Dr. Boppart holds a joint appointment at the Beckman Institute for Advanced Science and Technology.
See curriculum vitae for information about awards, academic and professional honors, publications, and professional associations and certifications.